America’s first and only

3,260 mile

ultra relay run!

MS Run the US is dedicated to raising awareness and funds to support multiple sclerosis (MS) research, while also aiding those living with disability due to MS.

Apply To Run The Relay

Apply To Run The Relay

Our Ultra Relay is an epic cross-country relay run from CA to NY for multiple sclerosis, with a limited 19 spots each year! Want to a spot on the team? Become an Ambassador to partner with our mission! Join and be part of the first group considered for the next team!

Take On The Challenge

Take On The Challenge

Our Relay runners run 160 miles in 6 days. Can you do that in 6 weeks? The Hometown Challenge starts June 5th. Are you ready? Register today!


Every year we run across America and rally thousands in support to help STOP multiple sclerosis (MS)! This is our story and why we run for a reason. Join us!

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